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Breast Cancer Index (BCI) Is Changing Physician Behavior

BCI results changed physician treatment recommendations in 30% of patients1

Key Results from Prospective Decision-Impact Trials (Physician-Reported)1,2

In a prospective decision-impact study led by Yale University of 141 patients with early-stage, HR+ breast cancer on endocrine therapy for over 3.5 years, 30% of physician treatment recommendations regarding extended therapy changed after receiving a BCI result.1

In a prospective study of 96 estrogen receptor–positive (ER+) patients led by Yale University, over 25% of physician treatment recommendations related to EET changed after receiving the BCI result.2

  • BCI resulted in net decrease in recommendations for EET by 20%
  • Twice as many patients reported feeling “strongly comfortable” with the treatment decision after receiving their BCI test results
  • 3X as many physicians felt strongly confident in their treatment recommendations

~1/2 of Patients Reported:

  • A change in their treatment preference
  • Experiencing less anxiety (p=0.031), 13% had no change in anxiety

~2/3 of Patients Reported:

  • Decreased decisional conflict (p<0.001)
  • Knowing the results would make them more likely to be compliant with extended therapy
Read The Study

References: 1. Sanft T, et al. Breast Cancer Manag. 2019;8(1). 2. Sanft T, et al. Breast Cancer Res Treat. 2015;154(3):533‑541.

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